Course Catalog
KGI’s Master of Bioscience program integrates science, engineering and management. Students acquire broad knowledge during the first year and in-depth expertise during the second year of the MBS curriculum.
All Master of Bioscience students take a common set of courses during their first year. Second year MBS students may choose a focus track by selecting certain elective courses. The first-year courses are 300-level courses and are not included in the focus areas. Second-year ALS courses are at the 400 level. The second year courses, other than ALS 400 Team Masters Project, meet the requirements of one or more focus track. The focus track legend for each course indicates whether a course is applicable (indicated by blue dot) to a specific focus track and whether the course is specifically required (indicated by a red dot) for a focus track.
Course Descriptions
ALS 300
Molecular Biotechnology
Animesh Ray
Students will be exposed to the conceptual foundations of biotechnology and the role played by discoveries and applications of molecular biology principles in advancing biotechnology horizons. This is a case-based course in which students will read landmark original papers and patents that shaped biotechnology, and discuss these in the class.
ALS 301
Molecular Basis of Disease
Animesh Ray, Craig Adams, James C. Osborne, Ian Phillips
This course examines the role of genes, proteins and RNA in causing or combating diseases, and emphasizes the current conceptual and analytical tools that are brought to bear, and their limitations, on our understanding.
ALS 311
Bioinformatics
This course introduces basic mathematical and computational tools to understand genes and genomes.
ALS 320
Medical Diagnostics
Angelika Niemz
This course provides an overview of the in vitro diagnostics industry and will enable students to acquire the basic knowledge and skills needed to understand and ultimately design diagnostic assays and devices. Students will become familiar with the fundamentals of biomolecular recognition, assay development, engineering design, device fabrication, optics, fluid mechanics, and laboratory automation.
ALS 321
Medical Devices
Gail D. Baura
This course presents an overview of medical devices through the years, from historic breakthroughs to more recently developed devices associated with areas of high job growth.
ALS 330
Pharmaceutical Discovery
Molly B. Schmid
This course is designed to provide you with an understanding of how pharmaceutical and biotechnology companies discover new drugs. This course will focus on the discovery of small molecule drugs.
ALS 331
Bioprocess Engineering Principles
Matthew S. Croughan
Graduates in molecular biology, bioengineering, and many other fields can potentially take advantage of many exciting and lucrative career opportunities in biotechnology development, manufacturing, commercial operations, business development, licensing, and investment fund management.
ALS 333
Pharmaceutical Development
Larry Grill
This course follows course ALS 330 and together these course are designed to provide an understanding of how pharmaceutical and biotechnology companies discover, develop, and bring drugs to market. This course will focus on the development of drugs.
ALS 341
BioIndustry Ethics & Society
This 15-week course, will cover a number of ethical and broader social issues related to bioindustry, with the goal of familiarizing students with up-to-date thinking on these issues.
ALS 350
Finance and Accounting Principles
Luann Bangsund
The goal of the course is to gain an appreciation and understanding of the topics covered.
ALS 351
Corporate Finance
Luann Bangsund
The goal of this course is to develop a basic understanding of financial decision making.
ALS 352
Organizational Behavior
Michelle Bligh, Becky Reichard
The focus of this course is on the scientific study of behavioral processes in organizations. It highlights critical management issues involved in planning, organizing, controlling, and leading an organization. This course aims to strengthen students’ managerial potential by providing general frameworks, or “foundations,” for analyzing, diagnosing, and responding to complex organizational situations.
ALS 354
Bioscience Strategy
Jay I. Chok
This introductory course in strategy is designed to help you beat the odds by improving your ability to perceive and seize success formulas before others do.
ALS 359
Introduction to Market Assessment and Market Strategy
Steven Casper
The course will equip students with an understanding of conceptual frameworks in market strategy and market assessment with reference to bioscience industries.
ALS 360
Business/Science Communications
James C. Osborne, Linda Crans
This course is designed around four broad themes: effective writing, oral communications, teamwork and leadership. Classes will be a blend of interactive lectures, from faculty and industry executives, and workshops. Oral and written exercises will be coordinated with individual and team projects in ALS 320 and ALS 359, and students will participate in faculty and peer reviews to help each other improve professional skills.
ALS 400
Team Masters Project
Craig Adams, Luann Bangsund, Diana Bartlett, Gail D. Baura, Steven Casper, Jay I. Chok, Tim Cote, Matthew S. Croughan, Tina Etcheverry, Larry Grill, Anna Iwaniec Hickerson, David Margolese, Ian Phillips, Molly B. Schmid, James D. Sterling, David Vetterlein
The Team Masters Project (TMP) is the capstone activity for second-year Master of Bioscience (MBS) students and for Postdoctoral Professional Masters (PPM) students. It is assigned 2-course credits each semester for a total of 4 course credits and a passing grade in both semesters is required for graduation with an MBS or PPM degree.
ALS 401
Biotechnology-based Therapeutics
Larry Grill
This course will provide students with a background of the scientific basis of some key aspects of biotechnology based drug, biologic and vaccine design, discovery and development process. Students will learn about therapeutic and vaccine targets, and how the drugs and vaccines are designed, tested and produced.
ALS 406
High Throughput Technologies - Lab
Angelika Niemz
This hands-on lab course focuses on applications of laboratory automation and high throughput technologies in drug discovery, biomarker discovery & validation, and basic research.
ALS 407
Personal Genomics and Health
Animesh Ray
This course surveys the technology currently available for whole genome sequencing, the technical advancements that must occur before “$1,000 a genome” becomes a reality, the source and range of variations in human genomes, current methods and theories that associate variants with disease susceptibilities/drug responsiveness, their respective weaknesses, and ethical, legal, and business implications of personal genomics.
ALS 408
In Vitro Diagnostics
James C. Osborne
This course covers emerging, high impact, and high growth rate areas of the in vitro diagnostics industry such as novel immunoassay formats, diagnostic applications of flow cytometry, molecular diagnostics and pharmaco-genomics, personalized medicine and drug diagnostic co-development, point of care diagnostics in developed countries and in global health / limited resource settings, as well as micro-fluidics and nano-technology in diagnostics.
ALS 409
High Throughput Technologies Lecture
Angelika Niemz
This course focuses on the use of laboratory automation and high throughput technologies in small molecule drug discovery, biomarker discovery, and basic research.
ALS 418
Bio pharmaceutical Quality assurance and Control
Vince Anicetti
The primary goal of this course is to provide students with an advanced background in the principles and requirements of biopharmaceutical quality assurance and control. Through a series of lectures and case studies this course will teach the critical thinking and judgment skills that are needed for the development of quality systems and the resolution of product quality issues.
ALS 421
Mammalian Cell Biotechnology Laboratory
Matthew S. Croughan
This full-unit laboratory course provides hands-on experience with many of the techniques and principles taught in the complimentary lecture course, ALS 427.
ALS 422
Bioseparations Laboratory
This half-unit laboratory course provides hands-on experience with many of the techniques and principles taught in the complimentary lecture course, ALS 429.
ALS 423
Fundamentals of Commercial Biotech Operations
Rick Johnston
This course focuses on issues specific to operations in biotechnology, including high variability in process operations, the need for very high supply reliability (no patient goes without) as well as long cycle times for biotech manufacturing.
ALS 424
Business Operations
Tathagata Dasgupta
Operations Management is concerned with the production and delivery of goods and services to meet customers' demands. It is one of the central functions of every business, government agency, and non-profit organizations.
ALS 425
Diagnostic and Device Product Development
Anna Iwaniec Hickerson
This course covers technical and managerial aspects involved in the development and manufacturing of instruments used in the devices and diagnostics industry, through a combination of lectures and case studies, delivered by the course instructors and invited industry experts.
ALS 426
Medical Device Development and Market Release
Gail D. Baura
This course presents an overview of the Design Control process for product development, which is mandated by the Good Manufacturing Practices of the Food and Drug Administration (FDA). To complement Design Control, market release and post-market surveillance topics are also highlighted.
ALS 427
Mammalian Cell Technology
Matthew S. Croughan
The scientific, engineering, and practical industrial aspects will be presented in a series of lectures.
ALS 429
Bioseparations Engineering and Science
Matthew S. Croughan
Graduates in molecular biology, bioengineering, or many other fields can potentially take advantage of many exciting and lucrative careers opportunities in biotechnology development, manufacturing, commercial operations, quality assurance, regulatory affairs, business development, licensing, and investment fund management.
ALS 430
Advanced Pharmaceutical Discovery
Molly B. Schmid
This course should provide the student with a deeper understanding of how pharmaceutical and biotechnology companies discover new drugs, and how larger companies manage their drug discovery portfolios
ALS 432
Writing an Orphan Drug Designation
Ian Phillips, Tim Cote
This course will equip students with an understanding on how to write an orphan drug designation application. The course will begin with a FDA Workshop on September 13, 2010 on how to write an orphan drug designation application. This workshop will be held at KGI and conducted by Dr. Matthew Thomas from the FDA. Students will receive further information from Dr Phillips on how to write their own orphan drug applications.
ALS 433
Clinical Trials Design, Conduct and Strategy
This course will provide students with a more in-depth understanding of clinical trial design, conduct and strategy for therapeutic products.
ALS 434
Biostatistics
Mark Ghamsary
This half-course provides a basic primer in statistical methods commonly used in the design of clinical trials.
ALS 435
Medical Device and Biologics Regulatory Affairs
Gail D. Baura
This course examines the operational, strategic and commercial aspects of the regulatory approval process for new medical devices, biologics, and combination products in the United States.
ALS 437
Clinical Pharmacology I
Alan Rothfeld
The course attempts to provide a general framework on which to fit future specialized knowledge encountered during a career in the various biomedical fields.
Some of the subjects addressed are: underlying principles of pharmacology and clinical biology, assessing and weighing benefits and risks, how physicians select therapies for a given disorder, how side effects are assessed and dealt with, and how issues of cost and compliance are handled.
ALS 438
Clinical Pharmacology II
Alan Rothfeld
The course provides overviews of disease categories, issues of cost, marketing, and the clinical trial process.
ALS 450
Entrepreneurial Finance
Luann Bangsund
This course examines the sources of financing available to start-up companies as they progress thorough the different stages of a firm’s lifecycle. The course introduces methods of valuation used by venture capitalists and other investors when considering investing in early stage firms. The course also examines alternative exit strategies and the impact of each strategy on the entrepreneur and the investors.
ALS 452
Entrepreneurship Practicum
David Margolese
This course offers students the opportunity to assist in the process of technology transfer from KGI laboratory research to the commercial realm.
ALS 454
International Business and Global Health
Steven Casper
This course will equip students with tools to effectively understand global marketplace issues within the life sciences. The course has three broad aims.
ALS 455
Marketing Management
Jenny Darroch
This course focuses on marketing and its role within organizations. It introduces the marketing concept, examines its relationship to other functions in the firm and looks at techniques and frameworks used to examine marketing environments, understand consumer and organizational buying behavior, segment markets and position products, develop new products, manage existing products and promote, price and place products.
ALS 456
Advanced Strategy Knowledge Advantage from Networks
This course examines the role of networks within industries and within firms in allowing some companies to outsmart and outperform others.
ALS 457
Entrepreneurial Management
David Margolese
The course will be concerned with new venture (seed-stage) business formation and implementation issues that relate to conceptualizing, developing and managing successful new ventures. These issues include corporate governance, entrepreneurial financing, competition, negotiation of term sheets and special issues related to seed-stage firms concerning intellectual property and technology transfer.
ALS 458
Applied Entrepreneurship
Molly B. Schmid, David Margolese
The focus of this course is on the concepts and practice of creating a new business. The course has many components in our attempts to make it realistic and useful, and these can be collected into two major categories: identifying and evaluating business opportunities, and conceiving, writing, executing and defending a business plan.
ALS 460
Advanced Writing and Editing for Professional Publications
Ian Phillips
The course will consist of tutoring, lectures, small group writing, editing, and reviewing by the faculty advisor, and between the student team participants. The course requires dedicated focus to the chosen topic and a series of deadlines that must be met.
ALS 461
Phase 1 Clinical Trials
Molly B. Schmid
This course should provide students with a deeper understanding of the important role of Phase I studies in early pharmaceutical development. Students expand their knowledge of the business and scientific aspects of initiating first-time-in-human (FTIH) Phase I studies.
ALS 462
Introduction to US Food and Drug Law
Tim Cote
This course will provide students with broad general competencies in regulatory affairs for all FDA-regulated product classes (drugs, biologics and devices) throughout the product lifecycle (pre-clinical development, clinical development and post marketing).
ALS 470
Innovation Management
Joel West
The successful management of technological innovation is essential to the success of many life science businesses, whether in human therapeutics, medical devices or biofuels. This course examines firm strategies for creating sustainable competitive advantage in technology-based industries.