Mark Brown, PhDAdjunct Faculty, KGI | Senior Scientist, Claremont Biosolutions
Parasitology, Molecular Biology, Virology, Bacterial Pathogenesis, Protein Biochemistry, Protein Structure, Bioinformatics, Proteomics, Genomics, Diagnostic Assay Development, Nucleic Acid Testing
The focus of this course is on the concepts and practice of creating a new business. The course has many components in our attempts to make it realistic and useful, and these can be collected into two major categories: identifying and evaluating business opportunities, and conceiving, writing, executing and defending a business plan.
Schneider RE, Brown MT, Shiflett AM, Dyall SD, Hayes RD, Xie Y, Loo JA, Johnson PJ. The Trichomonas vaginalis hydrogenosome proteome is highly reduced relative to mitochondria, yet complex compared with mitosomes. Int J Parasitol. 2011 Nov;41(13-14):1421-34.
Brown MT, Goldstone HM, Bastida-Corcuera F, Delgadillo-Correa MG, McArthur AG, Johnson PJ. A functionally divergent hydrogenosomal peptidase with protomitochondrial ancestry. Mol Microbiol. 2007 Jun;64(5):1154-63.
Carlton JM, Hirt RP, Silva JC, Delcher AL, Schatz M, Zhao Q, Wortman JR, Bidwell SL, Alsmark UC, Besteiro S, Sicheritz-Ponten T, Noel CJ, Dacks JB, Foster PG, Simillion C, Van de Peer Y, Miranda-Saavedra D, Barton GJ, Westrop GD, Müller
S, Dessi D, Fiori PL, Ren Q, Paulsen I, Zhang H, Bastida-Corcuera FD, Simoes-Barbosa A, Brown MT, Hayes RD, Mukherjee M, Okumura CY, Schneider R, Smith
AJ, Vanacova S, Villalvazo M, Haas BJ, Pertea M, Feldblyum TV, Utterback TR, Shu CL, Osoegawa K, de Jong PJ, Hrdy I, Horvathova L, Zubacova Z, Dolezal P, Malik SB, Logsdon JM Jr, Henze K, Gupta A, Wang CC, Dunne RL, Upcroft JA, Upcroft P, White O, Salzberg SL, Tang P, Chiu CH, Lee YS, Embley TM, Coombs GH, Mottram JC, Tachezy J, Fraser-Liggett CM, Johnson PJ. Draft genome sequence of the sexually transmitted pathogen Trichomonas vaginalis. Science. 2007 Jan 12;315(5809):207-12.
Mukherjee M, Brown MT, McArthur AG, Johnson PJ. Proteins of the glycine decarboxylase complex in the hydrogenosome of Trichomonas vaginalis. Eukaryot Cell. 2006 Dec;5(12):2062-71.
Mukherjee M, Sievers SA, Brown MT, Johnson PJ. Identification and biochemical characterization of serine hydroxymethyl transferase in the hydrogenosome of
Trichomonas vaginalis. Eukaryot Cell. 2006 Dec;5(12):2072-8.
Dyall SD, Brown MT, Johnson PJ. Ancient invasions: from endosymbionts to organelles. Science. 2004 Apr 9;304(5668):253-7. Review.
Brown MT, McBride KM, Baniecki ML, Reich NC, Marriott G, Mangel WF. Actin can act as a cofactor for a viral proteinase in the cleavage of the cytoskeleton. J Biol Chem. 2002 Nov 29;277(48):46298-303.
Mangel WF, Brown MT, Baniecki ML, Barnard D, McGrath WJ. Prevention of viral drug resistance by novel combination therapy. Curr Opin Investig Drugs. 2001 May;2(5):613-6. Review.
Mangel WF, McGrath WJ, Brown MT, Baniecki ML, Barnard DL, Pang YP. A new form of antiviral combination therapy predicted to prevent resistance from arising, and a model system to test it. Curr Med Chem. 2001 Jul;8(8):933-9.
McGrath WJ, Abola AP, Toledo DL, Brown MT, Mangel WF. Characterization of human adenovirus proteinase activity in disrupted virus particles. Virology. 1996 Mar 1;217(1):131-8.
Mangel WF, Toledo DL, Brown MT, Martin JH, McGrath WJ. Characterization of three components of human adenovirus proteinase activity in vitro. J Biol Chem. 1996 Jan 5;271(1):536-43.
|Mark Brown, PhD|