Contact UsAngelika Niemz
535 Watson Drive
Claremont, CA 91711
Phone: (909) 607-9854
Email: angelika_niemz[at symbol]kgi.edu
General capabilities in our laboratory include bioassay development, nucleic acid amplification with real time monitoring (isothermal and qPCR), nucleic acid lateral flow, bioassay optimization using Design of Experiments (DOE), high throughput automated liquid handling, customized computational tools for assay design and data evaluation, characterizing enzymatic reactions through experiments and numerical modeling, engineering design, standard machining, rapid prototyping, and injection molding.
The Niemz Group laboratory has approximately 1200 sq. ft. of total laboratory space divided into separate rooms for pre and post amplification, and a separate BSL2 laboratory for handling of infectious agents. The laboratory is equipped with two chemical fume hoods, two biosafety cabinets, 3 combination workstations, 3 dead air boxes, instrumentation for real time amplification and lateral flow detection, plus other standard lab instrumentation for routine molecular biology / molecular diagnostics.
In addition, KGI's Institutional Laboratory Support (ILS) provides core laboratory space, instrumentation, and services accessible to all researchers working at KGI. In particular, fabrication of devices for infectious disease diagnosis is performed in the design and fabrication facility, equipped with a Morgan Industries Injection Molding Press, Roland MDX-40 CNC Mill, Stratasys/Dimension SST768 rapid prototyping machine, Sherline/Flashcut 2000 CNC milling machine and 4400 CNC lathe controlled by a PC running SolidWorks CAD software and VisualMill 4.0CAM software. High throughput assay optimization and sequence screening is performed in the Laboratory Automation Center, equipped with a Beckman Coulter Biomek FXP Liquid Handler with 8-span, 96-well, and 384-well heads.