Students may focus their studies further by choosing one of four concentrations.
The Translational Research Thesis concentration is designed to give students a panoramic perspective of the translation of a basic research idea into a pragmatic or advantageous product for the biopharmaceutical industry, academia, or healthcare fields.
Why is Translational Research Important?
Despite landmark breakthroughs in the fields of drug discovery development, there are tens of thousands of diseases without any treatments or cures. Translational scientists partner with interdisciplinary teams of pharmacists, bioinformaticists, engineers, and others by taking basic discoveries in disease causation and transforming them into new drugs, devices, and diagnostic interventions. Translational research allows scientists to utilize a “bench to bedside” perspective in the development of new medications, diagnostic tools, and treatment strategies.
80-90% of drug development research projects fail before they get tested on humans.
For every drug that ultimately receives approval from the U.S. Food and Drug Administration, some 5,000 to 10,000 compounds don’t make it through the process.
Why pursue the Translational Research Concentration?
Translational Research Thesis concentration students participate in curriculum that is both diverse and interdisciplinary to prepare them to meet the demands of industry as well as areas of research deficit.
Students will build a strong foundation for future careers and academic pursuits in:
Clinical or academic research laboratories
Biotechnology and biopharmaceutical industries
Doctoral or professional degrees
Past and current Translational Research Thesis concentration projects include:
Discovery of amodiaquine-mediated synthetic lethality
Rapid automated pathogen diagnosis and reporting
discovery and characterization of small-molecule inhibitors of peroxiredoxin asp f3 in aspergillus fumigatus
GWAS-identified variations and their role in colon cancer etiology
CNS drug delivery
Low-cost vaccines for diseases that are problematic in developing countries
Identification of specific pathogenic or environmental triggers causing autoimmune diseases
Red blood cell trafficking in brain endothelial cells
Point of care diagnosis of chlamydia trachomatis, neisseria gonorrhoeae, and dengue virus infections
Neuronal loss in Parkinson’s and Alzheimer’s disease
Translational Research Thesis students will have the opportunity to conduct research at the USDA Western Regional Research Center within the following project areas:
Produce Safety and Microbiology Research
Healthy Processed Foods Research
Crop Improvement and Genetics Research
Foodborne Toxin Detection and Prevention Research
Invasive Species and Pollinator Health
Plant Gene Expression
More information on the research project areas can be found on the USDA website.
Our Faculty and Research Labs
Molecular Basis of Human Disease
Engineering, Medical Diagnostics, and Devices
Sociology, Innovation & Entrepreneurship
Course Offerings in the Translational Research Thesis Concentration – 15.0 units
Students are required to identify their thesis capstone project site during their first year of studies and must commit to a minimum of 18 hours per week to work on their thesis.
The Clinical Research Thesis concentration is designed to give students the ability to identify and problem solve healthcare-related issues, which in turn allows them to provide solutions in increasing healthcare access, improving patient outcomes, and other quality improvement needs.
Students apply research methods learned to solve healthcare issues in our partner clinical sites. In partnership with COPE Health Solutions, KGI graduate students complete their Clinical Research Thesis projects within one or more of the hospital sites within the COPE Health Scholars program.
Graduates of this concentration are uniquely positioned for future careers as medical researchers (clinical and academic), hospital administrators, or for the pursuit of doctoral studies or a medical or healthcare professional degrees. Students have the opportunity to conduct research in the areas of nosocomial infections, blood stewardship and usage, antibiotic stewardship, ICU cost control, staff performance, pain management, and case costs.
Through this research project, students will actively engage in projects that align with their field of study and learn from their on-site advisor how to identify hospital and/or health system needs to provide solutions to address gaps in quality and patient outcomes. Students will be assisting in data collection and statistical analytics, as well as tracking progress of existing or pending hospital projects. Students will not be assisting with hands-on patient care or delivery, but instead gain exposure to various careers in healthcare by going participating in rounds with nurses, doctors, and/or hospital administrators to gather the necessary data for their focused project.
Course Offerings in the Clinical Research Thesis Concentration – 16.5 units
Students planning to pursue the Clinical Research Thesis concentration must apply to participate in the program through the KGI-COPE application website. One of the prerequisites to participate in the program is enrollment in the ALS 495: Research Thesis course by the end of May.
Students must dedicate a minimum of 18 hours/week to work on their thesis.
Sample Project Topics
Nursing/Infection Prevention Departments
Antibiotic Stewardship Program
Documented indication of every transfusion
ICU Cost Control
Ventilator weaning and associated ICU protocols
Physician feedback on performance
Analysis of components of high cost/high volume procedures
Examples of hospital site placements
Adventist Health Bakersfield (AHBD) – Bakersfield, CA
Adventist Health Glendale (AHGL) – Glendale, CA
Adventist Health Simi Valley (AHSV) – Simi Valley, CA
Adventist Health White Memorial (AHWM) – East Los Angeles, CA
California Hospital Medical Center (CHMC) – Downtown Los Angeles, CA
Citrus Valley Health Partners (CVHP) – Covina, West Covina, and Glendora
Hoag Memorial Hospital Presbyterian (Hoag) – Newport Beach, CA
Kaiser Permanente Irvine (KPI) – Irvine, CA
Kaiser Permanente Riverside (KPR) – Riverside, CA
Kaiser Permanente South Bay (KPSB) – Harbor City, CA
Riverside Community Hospital (RCH) – Downtown Riverside, CA
Francis Medical Center (SFMC) – Lynwood, CA
John’s Regional Medical Center (SJRMC) – Oxnard & Camarillo
Joseph Hospital of Orange (SJO) – Orange, CA
Mary Medical Center (SMMC) – Long Beach, CA
Clinical Research Thesis Requirements
Complete training on regulatory and compliance-related issues (HIPAA, emergency response protocols, codes, etc.)
Clear background check
On-site interview at clinical site
Proof of immunization/test records
Proof of CPR certification
Proof of health insurance
The Public Health Research Thesis concentration prepares students to examine public health issues through a science lens, blending lab work with global and community health issues.
Why is Public Health Important?
Public health initiatives improve the lives of millions worldwide through addressing not only immediate health crises, but also workig to prevent future illness and injury. Public health professionals work tirelessly to ensure the health of the population as a whole by examining the root causes of disease and how to affect change on a large scale.
Areas of action and research in public health today include epigenetics, chronic disease, mental health, nutrition, and more.
Why pursue the Public Health Research Concentration?
Public Health Research concentration students participate in curriculum that builds their skills in the sciences and provides a strong foundation in public health principles.
Students will build a strong foundation for future careers in:
National, state, and local government
National and local health agencies and departments
Private health-based organizations and foundations
Research colleges and universities
Graduates will be able to pursue numerous careers in public health, including:
The Team Masters Project (TMP) concentration prepares students for working in cross-functional teams to work with sponsoring companies to solve real-life problems. The TMP ideally includes both business and technical aspects; for example, students may be asked to validate a new technology and to develop a strategy for market penetration of the technology. The actual deliverables for each TMP are negotiated by the student team and the company liaison.