Advances in genomics, proteomics, recombinant protein technology and structural biology have created opportunities and challenges for the biotech and pharmaceutical industries. This course will provide students with a background of the scientific basis of some key aspects of biotechnology based drug, biologic and vaccine design, discovery and development process. Students will learn about therapeutic and vaccine targets, and how the drugs and vaccines are designed, tested and produced. They will also learn about recently developed biological pharmaceuticals along with many of the current targets of pharmaceutical companies. The mechanism of many of the current biotechnology-based therapeutics will be discussed. In addition, the elements involved in the development a biotechnology company will be taught. A group project will be required in which each group will provide a short business plan for the development of a new drug. This course will consist of lectures, seminars and student presentations/group discussions. Environmental, ethical, regulatory, patent, economic and social issues related to biotechnology-based therapeutics will also be discussed.
Background knowledge in chemistry, biochemistry and molecular biology.
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