This course is intended to provide the trainee with a comprehensive curriculum on major topics in medical genetics. Various applications of genetics to human health, including studies of the inheritance of diseases in families, mapping of disease genes to specific locations on chromosomes, analyses of the molecular mechanisms through which genes cause disease, diagnosis and treatment of genetic disease, and genetic counseling, in which information regarding risks, prognoses, is communicated to patients and their families. This course will also cover the social implications of genetic disease and diagnosis. These principles will be illustrated using examples from clinical practice. Emphasis in lectures will be placed on molecular medicine with discussion of the most up-to-date clinical diagnostics and therapeutics.(GENE 380)
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