This course will explore the structure and function of the human genome. This course will begin by examining the sequence of the human genome and the dynamic structure of chromatin in human cells. It will also focus on technologies used to determine the DNA sequence and functional state of chromatin regions in living cells, including next generation sequencing, GWAS, and ChIP-seq. Furthermore, students will explore genome-wide data sets in order to predict phenotypes in populations and individuals. Variation in the population will be explored for the purposes of mapping complex traits, variant curation and genetic anthropology.