This course explores the structure and function of the human genes and the connection of genotype to phenotype. The scope of this course will include DNA structure, replication, and repair, the cell cycle, and gene expression and regulation. Mendelian and non-Mendelian inheritance will be discussed on the scale of individuals and populations. We will examine the role of mutation and variation in the etiology and diagnosis of disease, especially identifying and mapping causal genes. This course will also feature molecular biology techniques used to replicate DNA sequence, modify DNA molecules and genotype individuals.