The list of diseases with known molecular basis includes infectious diseases, cancers, metabolic diseases and mental health diseases. The idea that some diseases are due to genetic causes, a demonstration of which dates back to the early 20th Century, has now been expanded to include the possibility that all recognized human disorders may involve one or more genetic components of the patient. Since the genetic or epigenetic (in the case of identical twins) endowment of every human being on earth is different we must take seriously the concept of personalized medicine. This course examines the role of genes, proteins and RNA in causing or combating diseases, and emphasizes the current conceptual and analytical tools that are brought to bear, and their limitations, on our understanding.
ALS300A,B, or ALS407, or “upper level” (at least Junior level) undergraduate equivalent courses in Genetics, Cell Biology, Biochemistry, or Molecular Biology