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      • Doctor of Philosophy in Applied Life Sciences
      • Occupational Therapy Doctorate
      • Master of Business and Science
      • Master of Engineering in Biopharmaceutical Processing
      • Master of Science in Applied Life Sciences
      • Master of Science in Community Medicine
      • Master of Science in Human Genetics and Genetic Counseling
      • Master of Science in Human Genetics and Genomic Data Analytics
      • Master of Science in Medical Device Engineering
      • Master of Science in Physician Assistant Studies
      • Master of Science in Translational Medicine
      • Postbaccalaureate Premedical Certificate
      • Postbaccalaureate Pre-PA Certificate
      • Certificate in Bioscience Management
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      • Henry E. Riggs School of Applied Life Sciences
      • School of Medicine
      • School of Pharmacy and Health Sciences
      • Minerva Schools at KGI
      • Biocon Academy
    • Summer Programs
      • Application Boot Camp
      • Bioprocessing Summer Undergraduate Internship Training and Education
      • Botswana Summer Undergraduate Research Experience
      • Careers Beyond the Bench: Biotech Industry Summer Program
      • Clinical Genetics and Bioinformatics Summer Program
      • High School Summer STEM
      • Managing Science in Biotech for Postdocs
      • Medical Device Development Bootcamp
      • PA Summer Success Program
      • Pre-Occupational Therapy Program
      • Pre-Pharmacy Enrichment Program
      • Summer Explore Health Professions
      • Summer Undergraduate Research Experience
      • Undergraduate Summer Science Courses
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      • Faculty Directory
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      • Amgen Bioprocessing Center
      • Center for Biomarker Research
      • Center for Rare Disease Therapies
      • Center for Training in Applied Genomics
      • Science Heritage Center
    • Lab Safety & Support
      • Institutional Laboratory Support
      • Lab Safety Plans
      • Lab Safety Training
      • OSHA Lab Standard
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      • Alumni Success Stories
      • Spin-Off Companies
      • Dean’s List
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      • KGI Event Calendar
      • Club/Org Event Calendar
      • Commencement
      • Orientation
      • White Coat Ceremony
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      • Tuition Rates
      • Important Dates
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      • Student Accounts FAQ
      • 1098T FAQ
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ALS 330
Pharmaceutical Discovery

Semester: Fall
Credit(s): 1.5
Instructor(s): Mikhail Martchenko Shilman
More information
  • Description
  • Pre-Requisites
  • Learning Objectives

This course is designed to provide you with an understanding of how pharmaceutical and biotechnology companies discover new drugs. This course will focus on the discovery of small molecule drugs. (In other courses, you will learn about the discovery of biological drugs and vaccines). The course will follow the process of pharmaceutical drug discovery from selection of targets to discovery of a product candidate, and the characterization of that drug necessary for initiation of clinical trials. In the companion course (ALS-333), you will learn about the clinical development and commercialization of small molecule drugs, which importantly involves interactions with governmental agencies that regulate the commercialization of pharmaceutical products. In this course, you will learn the key steps that define how potential drugs are identified, optimized, and characterized in the preclinical setting and gain understanding of the key management challenges in the drug discovery process. The course will provide the terminology, timelines and practical examples for successfully understanding the challenges in progressing an idea for a drug from the earliest discovery stages through to clinical trials. Case studies from industry will be presented detailing companies and products that utilize state-of-the-art drug discovery technologies. This is a science course that freely intersperses business and regulatory issues into the lectures and assignments.

Mandatory for first-year MBS students
Recommended for PPM students interested in the pharmaceutical industry
ALS330 is required for ALS430

After completing this course, you should have:

  • A fundamental knowledge of the overall process of the discovery of small molecules for human health;
  • An appreciation of the scientific challenges facing drug discovery scientists at different stages in the drug discovery process;
  • An appreciation of the management challenges facing companies that aim to discover new pharmaceutical products;
  • Emerging ability to assess technical documents describing drug discovery project results and contribute to the assessment of a drug discovery project or company portfolio.

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