This course provides an introduction to the concepts involved in ensuring the safe, appropriate, and economical use of drugs in patient care. Students will develop a basic foundation in medication therapy management through an overview of the general principles of case-based problem-solving and a systematic approach to rational drug selection. Additionally, topics in clinical pharmacokinetics, special populations, and evidence-based medicine will be discussed. An integrated study of anatomy, pathophysiology, physical and laboratory assessment, pharmacology, therapeutics, clinical pharmacokinetics, patient care, alternative/complementary therapies, pharmacoeconomic issues, medication use in special populations, and review of pertinent drug literature as they relate to fluid and electrolyte homeostasis, and the renal system.