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Please join us for Uche Anyaduba’s Graduate Student Literature Seminar Presentation on:
Cancer treatment and drug development face significant challenges and obstacles due to the complexity and variability of cancer biology. Heterogeneity in tumors, innate drug resistance, non-therapeutic targets in some tumor cells, and adverse drug reactions are major roadblocks to effective treatment. Molecularly-targeted therapies are a potential solution to these challenges, as they can be designed to block or stimulate specific signaling pathways in cancer cells. At various stages of drug development and patients’ treatment journey, biomarkers advance clinical cancer therapeutics. Identifying predictive biomarkers is crucial to distinguish patient populations likely to benefit or experience adverse effects from targeted therapies. In clinical practice, validated predictive biomarkers are identified using in vitro companion diagnostic devices, which provide critical information necessary for the safe and effective use of a corresponding therapeutic product. This review describes the different biomarkers that have been approved for marketing for several cancer types and summarizes the current and rapid-growing FDA List of Cleared or Approved Companion Diagnostic Devices.
Date: Thursday, April 20
Time: 12:00 – 1:00 p.m
Location: 121 Bldg. – 1111 Classroom Via Zoom (see link below)