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Please join us for KGI PhD student Jason Lee, Process Engineer II, Kite Pharma Ph.D. Literature Mastery presentation.
The development and approval of autologous CAR-T cell therapies places an increase demand on manufacturing capacity. There are 5 commercially approved autologous CAR-T cell products with over 500 cell therapies in development. Implementation of automation technologies can reduce the reliance on skilled manufacturing technicians, increase process robustness, and decrease variability. The foundation of understanding T cell behavior in various environments may affect growth, performance, efficacy, and ultimately patient response. Identifying and understanding mechanisms (e.g., shear stress, temperature shift, pH levels) and their effects will provide a foundation for future cell therapy processes and related equipment. Developing a scale-down shear device to simulate and predict the shear stress found in complex bioprocess equipment can shorten process development timelines and improve the throughput of screening of new technologies.
Date: Thursday, December 8, 2022
Time: 12:00 – 1:00 p.m.
Location: 535 Bldg. – 152 Classroom and Via Zoom (See Zoom Link in Outlook Invite)