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Join us for PhD in Applied Life Sciences student Christine Urrea speak about: Continuous Bioprocessing: Technology for Next Generation Biopharmaceutical Manufacturing
Current industry standards for producing biopharmaceuticals includes manual fed batch production with batch isolation and purification. Nonproductive hold up steps are common in batch processing which increase processing time and contributes to the high cost of production. Continuous bioprocessing has been considered a solution to current limitations of the manual batch production of biopharmaceuticals. It involves the intensification of individual processing steps by eliminating hold up steps through their continuous operation which results in advantages such as lower investment and production cost, higher equipment utilization, smaller facility footprint and increased manufacturing flexibility due to the increased volumetric productivity. Technologies such as Raman spectroscopy, perfusion cell culture and continuous chromatography are currently being explored as solutions for continuous biopharmaceutical manufacturing.