Research Seminar Speaker Series-Dr. Animesh Ray-“The Noncoding RNA SPRIGHTLY Drives a Frequent Childhood Brain Cancer by Forcing Exon-Skipping”

Please join us for this presentation by our own KGI Faculty member, Dr. Animesh Ray, Professor of Systems Biology and Genomics

Noncoding RNA (ncRNA) genes are even more conserved in evolution than are protein coding genes, suggesting that ncRNAs play important biological functions. One such ncRNA is SPRIGHTLY, which we had previously shown to be important for skin cancer. Now we show that this molecule also plays an important role in Group 4 medulloblastomas, a frequent type of childhood brain cancer. I shall describe how SPRIGHTLY causes cancer in the brain cell by messing with an epigenetic regulator downstream to a well-known signaling pathway. The connection between the skin and the brain is more than skin deep. Our recent publication on this topic is here: https://academic.oup.com/noa/article/4/1/vdac120/6653116

Date: Friday, November 11, 2022

Time:  12:00 – 1:00 p.m.

Location:   121 Bldg. – 1111 Classroom and Via Zoom (See Outlook Invite for Zoom Link)