Company: Unity Biotechnology
Liaison(s): Doug Rich
Unity Biotechnology (UB) is a company located in Brisbane, California that aims to develop products that will increase human life span by enhancing health during aging.
UB’s objective is to halt, slow or reverse age-associated diseases by uncovering underlying mechanisms that contribute to these diseases, and developing senolytic medicines as effective age-associated disease treatments.
UB endeavors to improve the pharmacokinetic half-life of their candidate protein therapeutic by fusion to an Fc human antibody domain that serves as a delivery carrier. In order to generate product candidates for biological studies, the Team Master’s Project team has designed gene constructs for the production of the chimeric proteins in yeast. Expression levels of the product by engineered yeast strains were analyzed using flasks and fermenters.