The Amgen Bioprocessing Center (ABC)  is the scientific and engineering infrastructure that KGI established in 2004 with a generous donation from the Amgen Foundation to bring together resources, people, and infrastructure with the sole purpose of educating scientists and engineers to manage complex biological process scale-up.  Today, our reputation as a world-class teaching and training center extends across and beyond USA.

The Center serves the community and biopharmaceutical industries by offering a full spectrum a training programs, which taken together bridges the gap between traditional degree programs in life sciences and engineering and skills needed by the bioindustry.

The focus of the Center’s research is on bioprocessing and scale-up of:

  • rDNA-based  biopharmaceuticals – e.g. complex proteins and monoclonal antibodies
  • Next generation biologics – e.g. gene therapy and stem cell therapeutics 

The work of the Center is highly industry focused and guided by a distinguished team of Amgen Bioprocessing Center Advisory Board (ABCAB) members.

Over 90% of the Center’s research is collaborative with industry, providing a superb and unmatched platform for our students to interact with and learn from industry leaders.

Facility and Process Design and Operation Capability

  • 3000ft2 whole bioprocess facility
  • Upstream and Downstream Unit Operations
  • Mammalian cell culture
  • Shake flask to scalable bioreactors
  • Microbial fermentation
  • Shake flask to scalable bioreactors
  • Primary recovery
  • Lab scale centrifuge, depth, and tangential flow filters
  • Bioseparation
  • Chromatography, precipitation, and crystallization
  • Formulation
  • Buffer exchange, processing of high viscosity formulations
  • Bulk API Presentation
  • Freeze-thaw operations
  • Stem cells
  • Capability Lab-scale bioreactors design and scale up of stem cells
  • Process and Product Characterization
  • Analytical, First Principles, DOEs, QBDs